The production was helmed by Guetta, Sindres and Vee.Guetta, in an interview for MTV News, said the collaboration with Akon came after they met during a performance of "When Love Takes Over" with Kelly Rowland.The lyrics of "Sexy Bitch" deal with the protagonist's infatuation with a woman.

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It was released as the second single from One Love internationally.

The song was serviced to mainstream and rhythmic crossover radios on 1 September 2009 in the United States, through Astralwerks, together with Capitol Records.

"Sexy Bitch" was released as the second single from One Love (2009), after the international success of "When Love Takes Over".

It was released worldwide as a digital promotional single, which preceded the release One Love, on 24 July 2009.

However, the song was more successful in Australia, where it logged the top position for seven weeks and lasted on the chart for 38 weeks.

"Sexy Bitch" showed similar standings in the European countries, continuing Guetta's mainstream success around the world.

"Sexy Bitch" showed the most longevity in Switzerland, where it logged 77 weeks on the singles chart.

The song reached a peak of number two, where it stalled for three consecutive weeks in October 2009.

"Sexy Bitch" replicated the chart success of the previous single in international territories.

In the Australasian countries, it reached the summit of the singles charts in Australia and New Zealand.

The song achieved commercial success worldwide, peaking inside the top five in several countries, including topping the charts in Australia, Austria, Canada, Germany, New Zealand, and the United Kingdom.