Her only Wimbledon warm up tournament was the 2012 UNICEF Open.She reached the quarterfinals before losing to eventual champion Nadia Petrova.

She reached the third round of the 2012 US Open, losing to Roberta Vinci.

At the Sydney Apia International, she defeated top 10 players Petra Kvitová, Sara Errani, and Angelique Kerber en route to the final, which she lost to Agnieszka Radwańska, notably failing to win a single game.

At the Qatar Total Open, Cibulková reached her first ever Tier I quarterfinal, defeating former world no.

1 Venus Williams in the third round, before losing to Agnieszka Radwańska in the quarterfinals.

Her win represents the first time a player has captured their maiden title at the Kremlin Cup.

Seeded 17th in the Australian Open, Cibulková lost her second-round match to Gréta Arn.

She lost in the first round at the 2012 Wimbledon Championships to Klára Zakopalová.

She defeated Marion Bartoli in straight sets to win the 2012 Mercury Insurance Open in Carlsbad, California, picking up the second title of her career.

Cibulková then reached the finals of the Barcelona Open, losing to Sara Errani.

At the French Open, Cibulková avenged her Miami loss to Azarenka, beating the world no. She subsequently reached the quarterfinals for the second time, but lost to Samantha Stosur.

Cibulková began the year by reaching the quarterfinals of the 2011 Brisbane International, where she lost to Petra Kvitová.