He has been nominated for four Academy Awards: Best Director for Being John Malkovich, and Best Picture, Best Original Screenplay and Best Original Song ("The Moon Song") for Her.

The Koufey persona appeared when Jonze, in character, filmed himself dancing to Fatboy Slim's "The Rockafeller Skank" as it played on a boom box in a public area.

Jonze then assembled a group of dancers to perform to Slim's "Praise You" outside a Westwood, California movie theater and taped the performance.

He is part owner of skateboard company Girl Skateboards with riders Rick Howard and Mike Carroll.

He co-founded Directors Label, with filmmakers Chris Cunningham and Michel Gondry, and the Palm Pictures company.

He is well known also for his music video collaborations with Weezer, Beastie Boys, and Björk.

He was also a co-creator and executive producer of MTV's Jackass. He is also part owner of skateboard company Girl Skateboards with riders Rick Howard and Mike Carroll. When he was in junior high and high school, Spiegel hung out at Rockville BMX, where the former owner Jay gave him his nickname "Spike Jonze" in reference to Spike Jones.

Scenes from his short were used in the music video to the album's title song, "The Suburbs".

A dystopian vision of suburbia in the near-future, the short was co-written by Jonze, Win Butler, and Will Butler.

Expanding on the themes of nostalgia, alienation, and childhood, the short premiered at the Berlin International Film Festival and saw its online premiere at MUBI on June 27, 2011.